tag:blogger.com,1999:blog-58490657847991967192011-07-30T14:33:14.160-07:00Description and instructions for use of the drug IsotretinoinAccutanehttp://www.blogger.com/profile/04203791388049531067noreply@blogger.comBlogger11100tag:blogger.com,1999:blog-5849065784799196719.post-62988502125118685412010-06-12T13:06:00.000-07:002010-06-23T02:56:22.083-07:00<b><a href="http://www.acne-vulgaris-accutane.blogspot.com/">Accutane</a>. Roaccutane.</b> <br /><br />Isotretinoin - retinoids (synthetic derivative of vitamin A) used to treat severe acne and other skin diseases. Isotretinoin is sometimes used as a means of chemotherapy for the prevention and treatment of certain types of skin cancer, in some cases - for the treatment of ichthyosis.<br /><br /><br /><br /><center><img src="http://jabiru.blog.lemonde.fr/files/2007/10/accutane.1193538823.jpg" /></center><br /><br /><i>Indications for use of the drug Isotretinoin</i> <br /><br />Severe forms of acne (nodullar, disfiguring acne), purulent hydradenitis, severe forms of rosacea (acne rosacea), congenital ichthyosis, xeroderma pigmentosum. Retinoids are also used to treat severe forms of some chronic dermatoses (psoriasis).<br /><br /><i>Application</i> <br /><br />Isotretinoin treatment prescribed by your doctor and held under its control. <br /><br />Dosage is calculated based on disease severity and patient's weight. The highest daily dose of 0,5-2,0 mg / kg / day (usually 0,5-1,0 mg / kg / day) in two steps. The treatment lasts 4-6 months. A second course of isotretinoin is appointed in the relapse of acne, but not earlier than two months after the primary course.<br /><br /><i>Side effects</i> <br /><br />Excess of higher doses of the drug can cause side effects: dry skin, lips and mucous membranes, infection of the epidermis, cheilitis, itch, skin peeling, lihoradochye state, erythema, photosensitivity, nosebleeds, dry and irritated eyes, conjunctivitis, eye irritation when wearing contact lenses, hyperlipidemia, increase in liver enzymes, headache, hair thinning, myalgia and / or arthralgia. <br /><br />Also reported the following side effects after prolonged use of isotretinoin: alopecia, arthralgia, worsening of night vision (night blindness), keloid, diseases of the bone system.<br /><br /><i>Pregnancy and lactation</i> <br /><br />Acceptance of retinoids during pregnancy can cause serious fetal malformations, miscarriage, premature birth and neonatal death, even if during pregnancy the drug was taken in small doses and a short time. Women who breast-feeding should not take isotretinoin, as it is unknown whether it could harm the child.<br /><br /><i>Psychological effects</i> <br /><br />In addition to anxiety, some studies indicate that male patients increases the sensitivity to testosterone and manifest the attendant psychological effects such as irritability, excessive self-confidence and increased sexual desire. It should be noted that these symptoms were noted for over a month after the end of therapy.<br /><br /><i>Drug Interactions</i> <br /><br />Shared use of isotretinoin with tetracycline antibiotics or vitamin A is not recommended. Combined use of isotretinoin with tetracyclines significantly increases the risk of growth of intracranial pressure, increases the risk of toxic effects of vitamin A. The combined use of isotretinoin and methotrexate increases the hepatotoxicity, the use of a combination of these drugs must be under strict medical supervision for the possible side effects and liver function. <br />Cautions <br /><br />Patients undergoing treatment isotretinoin are not allowed to donate blood for at least a month after treatment.<br /><br /><i>Holidays drug from pharmacies</i> <br /><br />Isotretinoin belongs to the means of prescription.<div class="blogger-post-footer"><img width='1' height='1' src='https://blogger.googleusercontent.com/tracker/5849065784799196719-6298850212511868541?l=accutanepill.blogspot.com' alt='' /></div>Accutanehttp://www.blogger.com/profile/04203791388049531067noreply@blogger.com0